Diagnostic Immunopathology

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The updated and substantially expanded Second Edition features 22 all-new chapters on state-of-the-art immunopathologic testing techniques and the use of these techniques in diagnosis of immunopathologic diseases, immunodeficiencies, organ transplant rejection, and neoplasia. The expanded section on immunopathologic diseases includes new chapters on vasculitis, dysproteinemias, and diseases of the liver, lung, and nervous system. A new section on immunodeficiencies includes a classification system, an updated chapter on inherited immunodeficiencies, a discussion of the immunologic consequences and immunopathogenesis of AIDS, a description of the key diagnostic tests for HIV-induced diseases, and new chapters on opportunistic infections and immunodeficiency-related neoplasia. Coverage of organ transplantation, which was limited to the kidney in the First Edition, now encompasses all the kidney, heart, liver, lung, pancreas, and bone marrow. The section on neoplasia includes new chapters on oncogenes, bone and skin tumors, and the molecular biology of leukemias and lymphomas. Other new chapters in the Second Edition cover adhesion molecules, the complement system, lymphocyte functional assays, and in situ hybridization. Nearly 500 illustrations, including over 200 in full color, complement the text.