Esta serie se adentra en las profundidades del espacio, donde la humanidad establece el primer contacto con inteligencia extraterrestre a través de misteriosas señales. El conocimiento descubierto, descifrado de una computadora extraterrestre, abre una Caja de Pandora de la comprensión humana. La ciencia y la tecnología son llevadas a sus límites, pero también enfrentan una amenaza que podría poner en peligro la propia existencia de la humanidad.
A new radio telescope picks up from the constellation of Andromeda a complex series of signals which prove to be a programme for a giant computer. After the computer is built it begins to relay information from Andromeda. Scientists find themselves possessing knowledge previously unknown to mankind, knowledge that could threaten the security of human life itself.
The Andromeda Breakthrough is a sequel to the popular BBC TV science fiction serial A for Andromeda, written by Fred Hoyle and John Elliot. Kidnapped by Intel, John Fleming, the hero of the first serial, and Andromeda, the artificially constructed human, are brought to Azaran, a small Middle Eastern country, where a duplicate of the machine he designed has been built by Intel. After many dangers, he finds both the reason for the original message having been sent and the means to bring the machine under human control.