Molecular Mechanisms of Cancer

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The book delves into the complexities of cancer, exploring its diverse clinical presentations and questioning the classification of malignancies as a single disease entity. It emphasizes the role of oncogenes and tumor-suppressor genes in malignant transformation and introduces the concept of metasuppressor genes as a protective mechanism. The text discusses the molecular mechanisms of growth control, senescence, and metastasis, highlighting the significance of telomerase in cancer cell behavior and its activation through growth factor signaling.