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Set against the backdrop of Silicon Valley, the narrative explores cutting-edge research in human reproductive biology. Renu Krishnan, an Indian-born scientist, uncovers the role of nitric oxide in treating erectile dysfunction, paralleling the development of Viagra. Meanwhile, her husband, Jephtah Cohn, pioneers a novel method for ovulation prediction. As familiar characters return from previous installments, the story weaves together themes of innovation and the ethical dilemmas in biotechnology, culminating in a thought-provoking conclusion to Djerassi's tetralogy.