Adult heart muscle cells

The book explores various aspects of isolated adult heart cells, detailing the development of experimental models and the characteristics of guinea-pig ventricular myocytes. It discusses methods for determining myocyte viability, the significance of sarcolemma-bound calcium, and the effects of anoxic injury on cardiac myocytes. The text covers non-invasive measurement techniques for cell surface receptors and the role of surface antigens in diagnosis. Additionally, it examines substrate utilization and lactate transfer in myocytes, as well as the insulin receptor's function in heart muscle cells. The book includes insights into the adhesion of cardiac myocytes to extracellular matrix components and the formation of intercellular contacts in culture. It also addresses long-term primary cultures of human and rat cardiomyocytes and their morphological dedifferentiation when cocultured with hepatocytes. Electrophysiological properties, including the effects of cyanide on K-currents and ATP-dependence of K+-channels, are discussed. The correlation between catecholamine-induced damage and lipid peroxidation in heart cells is examined, alongside the influence of anoxia on lipid probe diffusion in plasma membranes. Summaries of symposium discussions and abstracts from a poster session on the adult myocyte model are also included, providing a comprehensive overview of current research in cardiac myocyte studies.