Diagnostik und Therapie der erektilen Dysfunktion mit vasoaktiven Substanzen

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This comprehensive work delves into the intricacies of erectile dysfunction (ED), covering foundational aspects, diagnostic methods, and treatment options. It begins with ultrastructural findings related to ED and explores the unique innervation of the corpus cavernosum. The text discusses potential neurotransmitters involved in erection and highlights the SKAT test's role in diagnosis. Advanced imaging techniques, such as Doppler sonography, are examined for assessing penile artery function, alongside pharmacological evaluations like pharmako-cavernosometry and pharmako-cavernosography. The historical development of vasoactive substances for ED diagnosis and therapy is summarized, followed by insights into intracavernous pharmacotherapy, including the use of papaverine and its combinations. The work also addresses the side effects and risks associated with injection therapies, such as prolonged erection and cavernous fibrosis from long-term treatment. Additionally, the psychological and relational impacts of self-injection therapy on patients with chronic ED are discussed, alongside practical aspects like the use of the ANDROPEN injection aid. The text concludes with a review of expert opinions on ED and the application of vasoactive substances in both diagnosis and treatment, providing a thorough resource for understanding and managing erectile dysfunction.