Molecular and clinical implications for allergy in the 21st century

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Allergic disorders, especially asthma, are the focal point of this volume. Presenting the proceedings of the 20th Symposium of the Collegium Internationale Allergologicum, it reviews current concepts of allergic reactions, from the clinical and also the molecular biological perspective. An understanding of these areas has important implications for the study and management of allergy in the next century.Contributions discuss a comprehensive range of topics, from host-related factors in allergy - such as genetics and the molecular regulation of IgE production - to the pathogenesis and treatment of allergic diseases, including asthma. The characteristics of the inflammatory response are given special attention as are exciting new therapeutic approaches. These include the use of antibodies to IgE or T cell reactive peptides from cat allergen Fel d 1 to lessen allergic reactions.This compendium will prove of great practical value to allergists and physicians interested in understanding and treating allergic diseases or asthma.Basic scientists concerned with these disorders who need access to an up-to-date review of ideas on IgE regulation, as well as mast ceil, basophil or eosinophil physiology, will also find it useful.