Testosterone

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The first edition of "Testosterone: Action, Deficiency, Substitution" was published in 1990, and since then, our understanding of this crucial hormone has significantly evolved. The editors have produced a second extended edition to summarize both established and recent findings in the field, reflecting the substantial growth in knowledge, which has expanded the volume from 14 to 20 chapters. This updated edition includes comprehensive information on the biochemistry and metabolism of androgens, along with detailed insights into the molecular biology of the androgen receptor and its disorders. The role of testosterone in spermatogenesis is now more clearly defined, and the psychotropic effects of testosterone are better understood. Individual chapters explore testosterone's impact on various target organs, including the prostate, cardiovascular system, and musculoskeletal system. The pharmacology and clinical applications of testosterone, especially in male hypogonadism, have been expanded to include pharmacokinetic studies and various substitution modalities. Additionally, the physiological basis and clinical applications of testosterone in non-gonadal diseases, male senescence, hormonal male contraception, and transsexuality are discussed. The final chapter addresses the role of steroid biochemistry in tracking anabolic steroid abuse.