Coronary circulation and myocardial ischemia

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The coronary circulation is vital for maintaining myocardial viability. Unlike other organ circulations, insufficient coronary flow can lead to a rapid decline in quality of life and even sudden death. Together with the cerebral circulation, it is essential for sustaining life; however, the coronary circulation uniquely influences global blood flow, setting the initial state for the entire body. This critical role, along with the fact that coronary artery disease often impacts individuals in their productive years, has positioned heart researchers and clinicians at the forefront of medical research. Recent advancements in understanding coronary circulation have gained significant attention, particularly given the numerous clinical trials aimed at enhancing coronary flow in various disease states. This context underscores the relevance of the current monograph, which compiles papers from an international symposium—the fourth in a series focused on the Applied Physiology of the Peripheral Circulation. The selected papers highlight key advancements in cardiology and the coronary circulation, reflecting the latest insights and developments in these crucial fields.