Mouse genetics after the mouse genome

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Reprint Cytogenetic and Genome Research 2004, Vol. 105, No. 2-4 The house mouse holds a unique place among model organisms, representing an indispensable tool for many investigators, particularly in biomedical research. Mouse genetics encompasses nearly 100 years of research and culminated in the publication of the mouse genome sequence in 2002, from which the idea for this special issue arose. The issue features 37 peer-reviewed papers providing a wide-ranging overview of all major aspects of mouse genetics, from nuclear transfer and embryonic development to cancer, from reproduction to speciation and functional genomics technologies. Its aim is to present a suitable tool of investigation for the large population of researchers that use the mouse as a model animal. Covering a variety of topics, this publication will be a useful guide for scientists working in the fields of reproduction, development, evolution, cancer, toxicology, and cell biology as well as for beginners entering the world of mouse genetics.