Algae-Based Biopharmaceuticals

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This book serves as a vital reference on algae's role in biopharmaceutical production, offering insights into current achievements and future prospects in this biotechnological field. It details the technology and progress made in algae-based biopharmaceuticals, highlighting algae as promising hosts for recombinant protein production due to their low cost, rapid growth, extensive biosynthetic capabilities, and lack of human pathogens, which present significant advantages over bacterial and mammalian systems. The first chapter analyzes algae's features as production hosts, focusing on cost, biosynthetic potential, and safety. The second chapter discusses genetic engineering tools specific to algae, comparing nuclear and chloroplast-based expression methods regarding biosynthetic benefits and gene expression complexities. Chapters 3 to 7 present the latest advancements in producing various biopharmaceuticals from algae species. While the primary focus is on biopharmaceuticals, chapter 8 addresses nutraceuticals derived from genetically-engineered algae strains. The final chapter reviews current developments and outlines challenges, emphasizing future prospects such as optimizing large-scale production in bioreactors, enhancing glycoengineering, improving nuclear expression, exploring new oral delivery methods, and establishing regulatory frameworks for technology transfer and approval of algae-derived biopharmaceuticals.