Interictal single-voxel 1H-proton magnetic resonance spectroscopy of the temporal lobe in dogs with idiopathic epilepsy

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Single voxel proton magnetic resonance spectroscopy is a promising diagnostic tool for use in dogs with idiopathic epilepsy und structurally normal brain. We did not observe variations in the investigated metabolite ratios in the IE group compared to the controls. Moreover, no age and sex related differences in metabolite ratios were noted. However, there is strong evidence for a relation between metabolite ratios and the time from the last seizure. Our data strongly suggests, that further MRS studies should be obtained on dogs in the ictal period. Magnetic resonance spectroscopy presents an additional value for the diagnosis of the canine idiopathic epilepsy and could help to localize the epileptogenic region in the future.