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Dependency and Structure Modelling (DSM) techniques support the management of complexity by focusing attention on the elements of a complex system and how they are related to each other. The DSM perspective can assist in understanding, designing and optimising complex systems – including products, processes and organisations. This volume comprises peer-reviewed papers representing state-of-the-art in DSM research and applications. The papers were presented at the 13th International DSM Conference held in September 2011 in Cambridge, MA, USA.