Programmed Alternative Reading of the Genetic Code

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Focusing on the mechanisms of translation, this book delves into initiation, elongation, and termination processes in both prokaryotes and eukaryotes. It examines error correction during translation, highlighting the structural basis for these mechanisms and the role of ribosomes in maintaining fidelity. The text also explores frameshifting, distinguishing between spontaneous and programmed shifts, and discusses specific genes and systems, such as the pifE gene in E. coli and retrotransposons in yeast, that illustrate these concepts in action.