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Details recent research on the ability of coagulation proteins/proteases to act as modulators of leukocyte effector functions, and potential implications in host defense and human disease. Coagulation is proposed as a response to injury, integrating the preservation of the hemostatic balance with host defense and immune-inflammatory responses. Part I introduces blood clotting mechanisms and their roles in leukocyte and vascular cell signaling. Part II describes the structure-function relationship of cellular receptors for blood clotting and examines fibrinolytic proteases and their role in signal transduction and effector cell responses. Distributed by Chapman & Hall. Annotation c. by Book News, Inc., Portland, Or.
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The Coagulation-Inflammation Interface: Coagulation Assembly on Leukocytes, Dario C. Altieri
- Idioma
- Publicado en
- 1997
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- (Tapa dura)
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