Copper Complexes as Antineoplastic Agents

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The exploration of metal ion complexes in anticancer drug development highlights their unique chemical reactivity and diverse coordination geometries, which allow for the creation of compounds not found in pure organic chemistry. The biological activity of these metal-based drugs is influenced by the types of ligands and the metal's oxidation state. Recent research has focused on therapeutic metal complexes, especially copper, due to its vital role in numerous copper-dependent enzymes essential for various biological processes.